Ceramide Inhibits L-Type Calcium Channel Currents in Rat Pinealocytes
نویسندگان
چکیده
منابع مشابه
cGMP inhibits L-type Ca2+ channel currents through protein phosphorylation in rat pinealocytes.
In this study, the effect of cGMP on the dihydropyridine-sensitive (L-type) Ca2+ current was investigated using the whole cell version of the patch-clamp technique in rat pinealocytes. Dibutyryl-cGMP (1 x 10(-4) M) induced a pronounced inhibition of the L-type Ca2+ channel current. The dibutyryl-cGMP effect was concentration dependent. Elevation of cGMP by nitroprusside had a similar inhibitory...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 1999
ISSN: 0013-7227
DOI: 10.1210/en.140.12.5682